CD14 (Monocyte/Macrophage Marker)

Product Specifications

Gene Name

[CD14]

NCBI Gene ID

929

Reactivity

Human. Others not tested.

Storage Conditions

Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a protein of 55kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

Other Gene Names

[CD14; CD14]

Short Name

[CD14]

Other Product Names

[monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14; monocyte differentiation antigen CD14; CD14 molecule; Myeloid cell-specific leucine-rich glycoprotein; CD_antigen: CD14]