Topoisomerase II alpha (Proliferation & Drug-Resistance Marker)
Selected Variant
MBS4380261-01
Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)
Product Specifications
Gene Name
[TOP2A]
NCBI Gene ID
7153
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
It recognizes a 170kDa protein, which is identified as topoisomerase II. shows no cross-reaction with Topoisomerase II or I. Topo II plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIï¡ is also implicated in drug resistance of tumor cells.
Other Gene Names
[TOP2A; TOP2A; TOP2; TP2A; TOP2]
Short Name
[Topoisomerase II alpha]
Other Product Names
[DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha; DNA topoisomerase II alpha; DNA topoisomerase II, alpha isozyme]
NCBI GI Number
19913406
NCBI Accession Number
NP_001058.2
NCBI GB Accession Number
NM_001067.3
Uniprot Accession Number
P11388
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