CD43 (T-Cell Marker)
Product Specifications
Gene Name
[CD43]
NCBI Gene ID
6693
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors of lymphoma.
Other Gene Names
[SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; CD43ct]
Short Name
[CD43]
Other Product Names
[leukosialin; Leukosialin; leukosialin; sialophorin; GPL115]
NCBI GI Number
71979937
NCBI Accession Number
NP_001025459.1
NCBI GB Accession Number
NM_001030288.3
Uniprot Accession Number
P16150
Available Sizes
Curated Selection
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