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PDCD1/PD1/CD279 (Programmed Cell Death 1)

Product Specifications

Gene Name

[PDCD1]

NCBI Gene ID

5133

Reactivity

Human. Others not known.

Storage Conditions

Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Other Gene Names

[PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1]

Short Name

[PDCD1/PD1/CD279 (Programmed Cell Death 1)]

Other Product Names

[programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; programmed cell death 1; CD_antigen: CD279]

NCBI GI Number

167857792

NCBI Accession Number

NP_005009.2

NCBI GB Accession Number

NM_005018.2

Uniprot Accession Number

Q15116

Available Sizes

Frequently Asked Questions

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