Lambda Light Chain (B-Cell Marker)
Product Specifications
Gene Name
[IGL]
NCBI Gene ID
449585; 3535; 3546
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Other Gene Names
[IGLV1-51]
Short Name
[Lambda Light Chain]
Other Product Names
[Immunoglobulin lambda variable 1-51; Immunoglobulin lambda variable 1-51; Ig lambda chain V-I region BL2]
NCBI GI Number
1063797053
NCBI Accession Number
P01701.2
Uniprot Accession Number
P01701
Available Sizes
Frequently Asked Questions
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