Single Donor Human Crohn's Disease Plasma

<strong>Single Donor Human Crohn's Disease Plasma</strong>_x000D_ <strong>Catalog number:</strong> B2013687_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 0.5-1.0 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Plasma_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20° C_x000D_ <strong>Keywords:</strong> Single Donor Human Crohn's Disease Plasma_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kong L, Pokatayev V, Lefkovith A, Carter GT, Creasey EA, Krishna C, Subramanian S, Kochar B, Ashenberg O, Lau H, Ananthakrishnan AN, Graham DB, Deguine J, Xavier RJ. The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon Immunity. 2023 Feb 14;56(2):444-458.e5._x000D_ 2: Sokol H, Landman C, Seksik P, Berard L, Montil M, Nion-Larmurier I, Bourrier A, Le Gall G, Lalande V, De Rougemont A, Kirchgesner J, Daguenel A, Cachanado M, Rousseau A, Drouet , Rosenzwajg M, Hagege H, Dray X, Klatzman D, Marteau P; Saint-Antoine IBD Network; Beaugerie L, Simon T. Fecal microbiota transplantation to maintain remission in Crohn's disease: a pilot randomized controlled study Microbiome. 2020 Feb 3;8(1):12._x000D_ 3: Zhang F, Mears JR, Shakib L, Beynor JI, Shanaj S, Korsunsky I, Nathan A; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium; Donlin LT, Raychaudhuri S. IFN-_ and TNF- drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation Genome Med. 2021 Apr 20;13(1):64._x000D_ 4: Ikezu T, Koro L, Wolozin B, Farraye FA, Strongosky AJ, Wszolek ZK. Crohn's and Parkinson's Disease-Associated LRRK2 Mutations Alter Type II Interferon Responses in Human CD14(+) Blood Monocytes Ex Vivo J Neuroimmune Pharmacol. 2020 Dec;15(4):794-800._x000D_ 5: Elleisy N, Rohde S, Huth A, Gittel N, Glass , Mller S, Lamprecht G, Sch_ffler H, Jaster R. Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn's disease World J Gastroenterol. 2020 May 14;26(18):2194-2202._x000D_ 6: Taka B, Mihaljevi S, Glava-Obrovac L, Kibel A, Suver-Stevi M, Canecki-Var_i S, Samard_ija M, Rajkovac I, Kova D, tefani M. INTERACTIONS AMONG INTERLEUKIN-6, C-REACTIVE PROTEIN AND INTERLEUKIN-6 (-174) G/C POLYMORPHISM IN THE PATHOGENESIS OF CROHN'S DISEASE AND ULCERATIVE COLITIS Acta Clin Croat. 2020 Mar;59(1):67-80._x000D_ 7: Muraro D, Lauffenburger DA, Simmons A. Prioritisation and network analysis of Crohn's disease susceptibility genes PLoS One. 2014 Sep 30;9(9):e108624._x000D_ 8: Molnar T, Hofner P, Nagy F, Lakatos PL, Fischer S, Lakatos L, Kovacs A, Altorjay I, Papp M, Palatka K, Demeter P, Tulassay Z, Nyari T, Miheller P, Papp J, Mandi Y, Lonovics J; Hungarian IBD Study Group. NOD1 gene E266K polymorphism is associated with disease susceptibility but not with disease phenotype or NOD2/CARD15 in Hungarian patients with Crohn's disease Dig Liver Dis. 2007 Dec;39(12):1064-70._x000D_ 9: Petersdorf EW, O'hUigin C. The MHC in the era of next-generation sequencing: Implications for bridging structure with function Hum Immunol. 2019 Jan;80(1):67-78._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23950992">10: Nieminen JK, Niemi M, Sipponen T, Salo HM, Klemetti P, F_rkkil_ M, Vakkila J, Vaarala O. Dendritic cells from Crohn's disease patients show aberrant STAT1 and STAT3 signaling PLoS One. 2013 Aug 7;8(8):e70738. </a>_x000D_ _x000D_ <strong>Products Related to Single Donor Human Crohn's Disease Plasma can be found at</strong> <a href="https://moleculardepot.com/product-category/Biofluids/"> Biofluids</a>