Butamben-d9
Product Specifications
UNSPSC Description
Butamben-d9 is the deuterium labeled Butamben. Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions[1][2].
Target Antigen
Calcium Channel; Isotope-Labeled Compounds; Potassium Channel; Sodium Channel
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling;Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C1=CC=C(N)C=C1
Molecular Weight
202.30
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Berg RJV, et, al. The local anesthetic n-butyl-p-aminobenzoate selectively affects inactivation of fast sodium currents in cultured rat sensory neurons. Anesthesiology. 1995 Jun;82(6):1463-73.|[3]Rampaart LJA, et, al. The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells. Anesth Analg. 2008 Jun;106(6):1778-83.|[4]Cereda CM, et al. Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model. J Liposome Res. 2017 Mar;27(1):74-82.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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