HCGRP- (8-37)
HCGRP- (8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor.
Product Specifications
CAS Number
[119911-68-1]
Product Name Alternative
Human α-CGRP (8-37)
UNSPSC
12352209
Target
CGRP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/HCGRP-_8-37_.html
Purity
99.60
Solubility
H2O : ≥ 20 mg/mL
Smiles
C([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](C(C)C)N)=O)[C@@H](C)O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)C)=O)=O)CC(C)C)=O)CC(C)C)=O)CO)=O)CCCNC(=N)N)=O)CO)=O)=O)=O)[C@@H](C)C)=O)C(C)C)=O)CCCCN)=O)CC(N)=O)=O)CC(N)=O)=O)=O)C(C)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)C)=O)CCCCN)=O)CO)=O)=O)[C@H](C)C)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCC3
Molecular Formula
C139H230N44O38
Molecular Weight
3125.59
References & Citations
[1]Chiba T, et al. Calcitonin gene-related peptide receptor antagonist human CGRP- (8-37) . Am J Physiol. 1989 Feb;256 (2 Pt 1) :E331-5.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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