MLCK inhibitor peptide 18
MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.
Product Specifications
CAS Number
[224579-74-2]
UNSPSC
12352209
Target
Autophagy; CaMK; Myosin
Type
Reference compound
Related Pathways
Autophagy; Cytoskeleton; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/MLCK_inhibitor_peptide_18.html
Purity
98.71
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[K][R]([Y]([Y][R][R](N)[K])[K])[K]
Molecular Formula
C60H105N23O11
Molecular Weight
1324.62
References & Citations
[1]Lukas TJ, et al. Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge. J Med Chem. 1999 Mar 11;42 (5) :910-9.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CaMK II
Available Sizes
Curated Selection
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