Ac-DEVDD-TPP
Ac-DEVDD-TPP is a porphyrin derivative that can be converted into D-TPP by caspase-3 cleavage and laser irradiation. The formed porphyrin nanofibers can effectively induce Apoptosis and Pyroptosis. Ac-DEVDD-TPP has antitumor activity[1].
Product Specifications
CAS Number
2950171-24-9
UNSPSC
12352209
Target
Apoptosis; Pyroptosis
Type
Peptides
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-devdd-tpp.html
Smiles
OC(C[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(NC1=CC=C(C=C1)/C2=C(C=C3)/N=C3/C(C4=CC=CC=C4)=C(C=C/5)\NC5=C(C6=CC=CC=C6)/C(C=C/7)=NC7=C(C8=CC=CC=C8)/C9=CC=C2N9)=O)=O)=O)=O)=O)=O
Molecular Formula
C68H64N10O14
Molecular Weight
1245.29
References & Citations
[1]Liu X, et al. Apoptosis-Amplified Assembly of Porphyrin Nanofiber Enhances Photodynamic Therapy of Oral Tumor. J Am Chem Soc. 2023 Apr 12;145 (14) :7918-7930.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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