Antituberculosis agent-12

Antituberculosis agent-12 (compound 3408) is a narrow-spectrum antituberculosis prodrug phosphate that has the ability to inhibit drug-resistant tuberculosis infection[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antituberculosis-agent-12.html

Smiles

O=C(N[C@@H]1C[C@@H](C)O[C@]2([H])[C@@]1(O)O[C@@]3(C)[C@]([C@@H](O)[C@H](NC)[C@H](O)[C@@H]3NC)([H])O2)CC4=NC=C(OP(O)(O)=O)C=C4

Molecular Formula

C22H35N4O11P

Molecular Weight

562.51

References & Citations

[1]Liu J, et al. Enhancing the therapeutic window for Spectinamide anti-tuberculosis Agents: Synthesis, Evaluation, and activation of phosphate prodrug 3408[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 112: 129934.