L-Ornithine L-aspartate

L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions[1][2][3][4].

Product Specifications

CAS Number

[3230-94-2]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-ornithine-l-aspartate.html

Purity

98.0

Solubility

H2O : 175 mg/mL (ultrasonic)

Smiles

N[C@@H](CC(O)=O)C(O)=O.N[C@@H](CCCN)C(O)=O

Molecular Formula

C9H19N3O6

Molecular Weight

265.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Sikorska H, et al. [Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency]. Pol Merkur Lekarski. 2010 Jun;28 (168) :490-5.|[2]Rose C, et al. L-ornithine-L-aspartate in experimental portal-systemic encephalopathy: therapeutic efficacy and mechanism of action. Metab Brain Dis. 1998 Jun;13 (2) :147-57.|[3]Najmi AK, et al. Effect of l-ornithine l-aspartate against thioacetamide-induced hepatic damage in rats. Indian J Pharmacol. 2010 Dec;42 (6) :384-7.|[4]Sisalli MJ, et al. L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson's Disease Models. Cells. 2022 Sep 17;11 (18) :2909.