Olanzapine-d3
Olanzapine-d3 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM) . Olanzapine is an atypical antipsychotic[1][2].
Product Specifications
CAS Number
[786686-79-1]
Product Name Alternative
LY170053-d3
UNSPSC
12352005
Hazard Statement
H301-H317-H319
Target
5-HT Receptor; Adrenergic Receptor; Apoptosis; Autophagy; Dopamine Receptor; mAChR; Mitophagy
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Purity
99.09
Solubility
10 mM in DMSO|DMSO : 20mg/mL (ultrasonic)
Smiles
[2H]C(N1CCN(C2=NC3=CC=CC=C3NC4=C2C=C(C)S4)CC1)([2H])[2H]
Molecular Formula
C17H17D3N4S
Molecular Weight
315.45
Precautions
P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501
References & Citations
[1]APPROVED AGREED-UPON LABELING.|[2]Olanzapine for Injection, powder, for solution for intramuscular use.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor;5-HT6 Receptor; D3 Receptor; mAChR1
Available Sizes
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