Human WEE1 Protein

<strong>Human WEE1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2014417_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 115 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> WEE1hu_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Matheson CJ, Backos DS, Reigan P. Targeting WEE1 Kinase in Cancer Trends Pharmacol Sci. 2016 Oct;37(10):872-881._x000D_ 2: Kong A, Mehanna H. WEE1 Inhibitor: Clinical Development Curr Oncol Rep. 2021 Jul 16;23(9):107._x000D_ 3: Ghelli Luserna di Ror A, Cerchione C, Martinelli G, Simonetti G. A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target J Hematol Oncol. 2020 Sep 21;13(1):126._x000D_ 4: Koh SB. The expanding role of WEE1 Cell Signal. 2022 Jun;94:110310._x000D_ 5: Shi L, Xue X, Tian H, Ye H, Wang H, Wang R, Liu Y, Zhang C, Chen Q, Sun L. WEE1 promotes endometriosis via the Wnt/_-catenin signaling pathway Reprod Biol Endocrinol. 2021 Oct 22;19(1):161._x000D_ 6: de Nonneville A, Finetti P, Birnbaum D, Mamessier E, Bertucci F. WEE1 Dependency and Pejorative Prognostic Value in Triple-Negative Breast Cancer Adv Sci (Weinh). 2021 Sep;8(17):e2101030._x000D_ 7: Li C, Shen Q, Zhang P, Wang T, Liu W, Li R, Ma X, Zeng X, Yin Y, Tao K. Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells J Exp Clin Cancer Res. 2021 Oct 8;40(1):315._x000D_ 8: Du X, Li J, Luo X, Li R, Li F, Zhang Y, Shi J, He J. Structure-activity relationships of Wee1 inhibitors: A review Eur J Med Chem. 2020 Oct 1;203:112524._x000D_ 9: Bukhari AB, Chan GK, Gamper AM. Targeting the DNA Damage Response for Cancer Therapy by Inhibiting the Kinase Wee1 Front Oncol. 2022 Feb 17;12:828684._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32120135">10: Elb_k CR, Petrosius V, Srensen CS. WEE1 kinase limits CDK activities to safeguard DNA replication and mitotic entry Mutat Res. 2020 Jan-Apr;819-820:111694. </a>_x000D_ _x000D_ <strong>Products Related to Human WEE1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>