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Cynomolgus PADI2 Protein, His Tag (MALS verified)

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.

Product Specifications

Background

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 77.6 kDa. The protein migrates as 75-85 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

A0A2K5TST4-1

Expression Region

Met 1 - Pro 665

Host

Insect Cells

Target

PADI2

Conjugation

Unconjugated

Tag

N-10xHis

Source

Cynomolgus

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Liquid

Buffer

PBS, pH7.4

Additives

Glycerol

Molecular Weight

77.6 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Host or Source

InsectCells

Species

Cynomolgus

Protein ID

A0A2K5TST4-1

Preservative

Glycerol

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