N6-Benzoyl-7’-OH-N-trityl morpholino adenine
N6-Benzoyl-7’-OH-N-trityl morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[956139-16-5]
Product Name Alternative
N-[9- (6-Hydroxymethyl-4-trityl-morpholin-2-yl) -9H-purin-6-yl]-benzamide
UNSPSC
12352005
Hazard Statement
H302
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n6-benzoyl-7-oh-n-trityl-morpholino-adenine.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C2N=CN([C@H]3CN(C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)C[C@@H](CO)O3)C2=NC=N1)C7=CC=CC=C7
Molecular Formula
C36H32N6O3
Molecular Weight
596.68
Precautions
P264-P270-P330-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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