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N6-Benzoyl-7’-OH-N-trityl morpholino adenine

Selected Variant

HY-W357200-01

Size: 100 mg

N6-Benzoyl-7’-OH-N-trityl morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

956139-16-5

Product Name Alternative

N-[9- (6-Hydroxymethyl-4-trityl-morpholin-2-yl) -9H-purin-6-yl]-benzamide

UNSPSC

12352005

Hazard Statement

H302

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n6-benzoyl-7-oh-n-trityl-morpholino-adenine.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=C2N=CN([C@H]3CN(C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)C[C@@H](CO)O3)C2=NC=N1)C7=CC=CC=C7

Molecular Formula

C36H32N6O3

Molecular Weight

596.68

Precautions

P264-P270-P330-P501

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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