L-Threonic acid (magnesium)

L-Threonic acid magnesium (Magnesium L-threonate) is the enantiomer of Threonic acid and the metabolite of vitamin C (HY-B0166) . L-Threonic acid magnesium is a magnesium supplementation, that improves the brain magnesium concentration, inhibits the activation of TNF-α/NF-κB signaling pathway. L-Threonic acid magnesium can be used in research of Alzheimer’s disease. L-Threonic acid magnesium is orally active[1][2].

Product Specifications

CAS Number

[778571-57-6]

Product Name Alternative

Magnesium L-threonate

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

NF-κB; TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis; NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-threonic-acid-magnesium.html

Purity

99.0

Solubility

H2O : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@H]([C@H](CO)O)C([O-])=O.O[C@H]([C@H](CO)O)C([O-])=O.[Mg+2]

Molecular Formula

C8H14MgO10

Molecular Weight

294.50

Precautions

H302, H315, H319, H335

References & Citations

[1]Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22 (1) :18-35 |[2]Liu X, et al. The causal role of magnesium deficiency in the neuroinflammation, pain hypersensitivity and memory/emotional deficits in ovariectomized and aging mice[J]. 2021.