Pomalidomide-CO-C7-NH-CO-C3-COOH
Pomalidomide-CO-C7-NH-CO-C3-COOH is a conjugate of a ligand for E3 ligase and a linker. Pomalidomide-CO-C7-NH-CO-C3-COOH can be used for synthesis of PROTAC degrader ARM165.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-co-c7-nh-co-c3-cooh.html
Smiles
O=C(O)CCCC(NCCCCCCCC(NC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)=O)=O
Molecular Formula
C26H32N4O8
Molecular Weight
528.55
References & Citations
[1]Kelly LM, et al., Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Nat Cancer. 2024 May 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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