IMP-2373

IMP-2373 is the activity-based probe (ABP) . IMP-2373 is a covalent pan- deubiquitinase (DUB) ABP to monitor DUB activity in physiologically relevant live cells[1].

Product Specifications

UNSPSC

12171500

Target

Deubiquitinase; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/imp-2373.html

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C#CC1=CC=C(CNC(C2=CC(C(C3CN(C#N)CC3)=O)=CN2C)=O)C=C1

Molecular Formula

C21H20N4O2

Molecular Weight

360.41

References & Citations

[1]Daniel Conole, et al. Discovery of a Potent Deubiquitinase (DUB) Small-Molecule Activity-Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells. Angew Chem Int Ed Engl. 2023, 62, 47.