IMP-2373
IMP-2373 is the activity-based probe (ABP) . IMP-2373 is a covalent pan- deubiquitinase (DUB) ABP to monitor DUB activity in physiologically relevant live cells[1].
Product Specifications
UNSPSC
12171500
Target
Deubiquitinase; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imp-2373.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CC1=CC=C(CNC(C2=CC(C(C3CN(C#N)CC3)=O)=CN2C)=O)C=C1
Molecular Formula
C21H20N4O2
Molecular Weight
360.41
References & Citations
[1]Daniel Conole, et al. Discovery of a Potent Deubiquitinase (DUB) Small-Molecule Activity-Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells. Angew Chem Int Ed Engl. 2023, 62, 47.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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