MTH1 degrader-1
MTH1 degrader-1, a MTH1 aTAG inhibitor, is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). MTH1 degrader-1 can be used for synthesis PROTAC aTAG 4531.
Product Specifications
CAS Number
2412987-06-3
UNSPSC
12352005
Target
DNA/RNA Synthesis; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mth1-degrader-1.html
Smiles
O=C(O)C1=CC=C(C2=C(F)C=C3N=CC(C(NC4CC4)=O)=C(NC5=CC=CC=C5)C3=C2)C=C1F
Molecular Formula
C26H19F2N3O3
Molecular Weight
459.44
References & Citations
[1]Veits G K, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity. Current Research in Chemical Biology, 2021, 1: 100010.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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