PI3K/AKT-IN-3
PI3K/AKT-IN-3 (compound 8C) can induce autophagy and apoptosis by inhibiting the PI3K/AKT signaling pathway. PI3K/AKT-IN-3 can be used in cancer research[1].
Product Specifications
CAS Number
2488891-30-9
UNSPSC
12352005
Target
Akt; Apoptosis; Autophagy; PI3K
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-akt-in-3.html
Smiles
COC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C([C@@H](C5)CC6=CN([C@@H]7[C@H](O[C@@H](N8C(NC(C(C)=C8)=O)=O)C7)CO)N=N6)=O)C)([H])CC4)C)([H])CC3)C)C)=O
Molecular Formula
C44H63N5O7
Molecular Weight
774.00
References & Citations
[1]Wang Q, Ma F, Wang J, Xu H, Li K, Cheng YY, Chen X, Qu S, Wei T, Hao X, Kong M, Xie C, Wang W, Wang Y, Jeong LS. Antitumor activity and transcriptome sequencing (RNA-seq) analyses of hepatocellular carcinoma cells in response to exposure triterpene-nucleoside conjugates. Eur J Med Chem. 2024 Jun 28;276:116635.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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