Menin-MLL inhibitor 31
Product Specifications
UNSPSC Description
Menin-MLL inhibitor 31 (compound 18) is a potent inhibitor of the menin MLL interaction with an IC50 value of 4.6 nM[1].
Target Antigen
Epigenetic Reader Domain
Type
Peptides
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/menin-mll-inhibitor-31.html
Solubility
10 mM in DMSO
Smiles
O=C1C2(CCC2)NC([C@@]3([H])N(CCC3)C([C@@H](NC([C@H](CCCC[C@H](N1)C(N4C[C@@H](CC4)C(N[C@@H](CCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](C)NC(C)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)CC7=CC(F)=CC=C7)=O)=O
Molecular Weight
1679.95
References & Citations
[1]Hao Lei, et al. Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia. J Med Chem. 2021 Nov 11;64(21):15519-15533.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10066/Menin-MLL-inhibitor-31-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10066/
Clinical Information
No Development Reported
CAS Number
2863656-86-2
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