Desmethylxanthohumol

Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.) . Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities[1][2].

Product Specifications

CAS Number

[115063-39-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/desmethylxanthohumol.html

Purity

99.66

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=C(O)C=C(O)C(C/C=C(C)\C)=C1O)/C=C/C2=CC=C(O)C=C2

Molecular Formula

C20H20O5

Molecular Weight

340.37

Precautions

H315, H319, H335

References & Citations

[1]Yuou Teng, et al. Synthesis and Antioxidant Evaluation of Desmethylxanthohumol Analogs and Their Dimers. Eur J Med Chem. 2017 Jan 5;125:335-345.|[2]Reinhard A.Diller, et al. 71-Desmethylxanthohumol from Hops, Chemistry and Biological Effects. Beer in Health and Disease Prevention, 2009, Pages 703-709.