LY2119620

LY2119620 is a high-affinity muscarinic M2/M4 receptor agonist.

Product Specifications

CAS Number

[886047-22-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/LY2119620.html

Purity

99.74

Solubility

DMSO : 67.5 mg/mL (ultrasonic)

Smiles

NC1=C(C(NC2CC2)=O)SC3=C1C(C)=C(Cl)C(OCC(N4CCN(C)CC4)=O)=N3

Molecular Formula

C19H24ClN5O3S

Molecular Weight

437.94

Precautions

H302, H315, H319, H335

References & Citations

[1]Croy CH, et al. Characterization of the novel positive allosteric modulator, LY2119620, at the muscarinic M (2) and M (4) receptors. Mol Pharmacol. 2014 Jul;86 (1) :106-15.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MAChR2; mAChR4

Available Sizes

Curated Selection

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