Anti-BACH1 Antibody
Rabbit Polyclonal Antibody specific to BACH1
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
BTB and CNC homolog 1, HA2303
Gene Name
BACH1
NCBI Gene ID
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=BACH1">BACH1</a>
UniProt
O14867
Cellular Locus
Nucleus
Host
Rabbit
Reactivity
Human
Immunogen
Peptide corresponding to aa 1233-1249 of the human BACH1 protein.
Target Antigen
Transcription regulator protein BACH1
Target
BACH1
Clonality
Polyclonal
Type
Antibody
Applications
WB
Field of Research
Cancer research
Purification Method
Purified by immunoaffinity chromatography
Concentration
Lot Specific
Dilution
Dilute in PBS or medium which is identical to that used in the assay system.
Format
Purified
Form
Liquid
Buffer
Phosphate Buffered Saline
Function
Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK (By similarity). Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498). {UniProtKB:P97302, PubMed:24035498}.
Additionnal Information
Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 81 kD is detected.
Storage Conditions
This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.
Specificity
This antibody recognizes human BACH1 protein, a member of the DEAH helicase family. BACH1 interacts with BRCA1, and mutations in BACH1 interfere with normal double-strand DNA break repair.
Formulation
PBS, pH 7.4.
Buffer pH
pH 7.4
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