ZZL-7
ZZL-7 is a fast-onset antidepressant agent. ZZL-7 works by disrupting the interaction between the serotonin transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN) . ZZL-7 can cross the blood-brain barrier readily. ZZL-7 can be used for the research of major depressive disorder (MDD) [1].
Product Specifications
CAS Number
[99141-91-0]
UNSPSC
12352211
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/zzl-7.html
Concentration
10mM
Purity
98.13
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC(C)[C@@H](C(OC)=O)NC([C@H](C)NC(C)=O)=O
Molecular Formula
C11H20N2O4
Molecular Weight
244.29
References & Citations
[1]Nan Sun, et al. Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN. Science. 2022 Oct 28;378 (6618) :390-398.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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