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ε-Poly-L-lysine (hydrochloride) (MV 2000-5000)

ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer[1][2][3][4].

Product Specifications

Product Name Alternative

Epsilon-polylysine (hydrochloride) (MV 2000-5000) ; ε-Polylysine (hydrochloride) (MV 2000-5000) ; ε-PL (hydrochloride) (MV 2000-5000)

UNSPSC

12352200

Target

Bacterial

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ε-poly-l-lysine-hydrochloride-mv-2000-5000.html

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

CNC([C@H](CCCCC)N)=O.[n].Cl

Molecular Formula

(C6H12N2O.ClH) n

Molecular Weight

2000-5000

References & Citations

[1]Wang Z, et al. Metabolomic Analysis of Biosynthesis Mechanism of ε-Polylysine Produced by Streptomyces diastatochromogenes. Front Bioeng Biotechnol. 2021 Jul 30;9:698022.|[2]Alemán A, et al. A novel functional wrapping design by complexation of ε-polylysine with liposomes entrapping bioactive peptides[J]. Food and Bioprocess Technology, 2016, 9: 1113-1124.|[3]Yingying M, et al. pH-Sensitive ε-polylysine/polyaspartic acid/zein nanofiber membranes for the targeted release of polyphenols. Food Funct. 2022 Jun 20;13 (12) :6792-6801.|[4]Zhou X, et al. Elaboration and characterization of ε-polylysine‑sodium alginate nanoparticles for sustained antimicrobial activity. Int J Biol Macromol. 2023 Aug 16;251:126329.|[5]Li Hua, et al. The modes of action of epsilon-polylysine (ε-PL) against Botrytis cinerea in jujube fruit. Postharvest Biology and Technology 147 (2019) : 1-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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