D (+) -Raffinose (pentahydrate)
D (+) -Raffinose pentahydrate is an orally active inhibitor of LecA (Kd = 32 μM) and GtfC. D (+) -Raffinose pentahydrate reduces cyclic diguanylate (c-di-GMP) by increased activity of a c-di-GMP specific phosphodiesterase. D (+) -Raffinose pentahydrate interferes with GTF function. D (+) -Raffinose pentahydrate decreases IL-4 and IL-5 mRNA. D (+) -Raffinose pentahydrate exhibits biofilm-inhibitory activity against Pseudomonas aeruginosa and Streptococcus mutans and inhibits allergic airway eosinophilia[1][2][3].
Product Specifications
CAS Number
[17629-30-0]
Product Name Alternative
D-Raffinose (pentahydrate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Endogenous Metabolite; Glucosylceramide Synthase (GCS) ; Interleukin Related; Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/D__addition__-Raffinose_pentahydrate.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OC[C@]1(O[C@H](CO)[C@@H](O)[C@@H]1O)O[C@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO[C@H]([C@@H]([C@@H](O)[C@H]3O)O)O[C@@H]3CO.O.O.O.O.O
Molecular Formula
C18H42O21
Molecular Weight
594.51
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
IL-4; IL-5
Available Sizes
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