YE6144
Product Specifications
UNSPSC Description
YE6144 is a prototypical interferon regulatory factor 5 (IRF5) inhibitor. YE6144 selectively suppresses IRF5 activity through inhibition of IRF5 phosphorylation[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ye6144.html
Solubility
DMSO : 70 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC[C@@H](CNC1=CC2=C(NN=C2/C=C/C3=CC=C(N4CCOCC4)N=N3)C=C1F)N.[H]Cl
Molecular Weight
447.94
References & Citations
[1]Ban T, et al. Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease. Nat Commun. 2021 Jul 19;12(1):4379.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150095/YE6144-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150095/YE6144-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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