Kasugamycin

Kasugamycin (Ksg) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1].

Product Specifications

CAS Number

[6980-18-3]

Product Name Alternative

Ksg

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/kasugamycin.html

Purity

99.82

Solubility

H2O : 7 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O

Molecular Formula

C14H25N3O9

Molecular Weight

379.36

References & Citations

[1]"Hong Zhang, et al. Simultaneous determination of kasugamycin and validamycin-A residues in cereals by consecutive solid-phase extraction combined with liquid chromatography-tandem mass spectrometry. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Mar;35 (3) :487-497. "