Fenobucarb-d3

Fenobucarb-d3 is the deuterium labeled Fenobucarb. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals[1][2].

Product Specifications

CAS Number

[2662756-72-9]

UNSPSC

12352005

Target

Apoptosis; Caspase; Cholinesterase (ChE) ; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Solubility

10 mM in DMSO

Smiles

O=C(NC([2H])([2H])[2H])OC1=C(C(CC)C)C=CC=C1

Molecular Formula

C12H14D3NO2

Molecular Weight

210.29

References & Citations

[1]Xiao-Yu Zhu, et al. Fenobucarb induces heart failure and cerebral hemorrhage in zebrafish. Aquat Toxicol. 2019 Apr;209:34-41.|[2]Zhu XY, et al. Fenobucarb-induced developmental neurotoxicity and mechanisms in zebrafish. Neurotoxicology. 2020 Jul;79:11-19.