Anti–BRD2 Polyclonal Antibody
<strong>Anti‚ÄìBRD2 Polyclonal Antibody </strong>_x000D_ <strong>Catalog number:</strong> B2019147_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> BRD-2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lee H, Nam J, Jang H, Park YS, Son MH, Lee IH, Eyun SI, Yang JH, Jeon J, Yang S. BRD2-specific inhibitor, BBC0403, inhibits the progression of osteoarthritis pathogenesis in osteoarthritis-induced C57BL/6 male mice Br J Pharmacol. 2024 Aug;181(15):2528-2544._x000D_ 2: Ma L, Wang J, Yang Y, Lu J, Ling J, Chu X, Zhang Z, Tao Y, Li X, Tian Y, Li Z, Zhang Y, Sang X, Lu L, Wan X, Zhang K, Chen Y, Yu J, Zhuo R, Wu S, Pan J, Zhou X, Hu Y, Hu S. BRD4 PROTAC degrader MZ1 exhibits anti-B-cell acute lymphoblastic leukemia effects via targeting CCND3 Hematology. 2023 Dec;28(1):2247253._x000D_ 3: Park IH, Yang HN, Jeon SY, Hwang JA, Kim MK, Kong SY, Shim SH, Lee KS. Anti-tumor activity of BET inhibitors in androgen-receptor-expressing triple-negative breast cancer Sci Rep. 2019 Sep 16;9(1):13305._x000D_ 4: Belkina AC, Blanton WP, Nikolajczyk BS, Denis GV. The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis J Leukoc Biol. 2014 Mar;95(3):451-60._x000D_ 5: Li JJ, Lu XY, Jia P, Zhu L, Wang A, Bu FT, Zhang YL, Huang C, Li J. O-alkyl and o-benzyl hesperetin derivative-1L attenuates inflammation and protects against alcoholic liver injury via inhibition of BRD2-NF-Œ∫B signaling pathway Toxicology. 2022 Jan 30;466:153087._x000D_ 6: Cribbs AP, Filippakopoulos P, Philpott M, Wells G, Penn H, Oerum H, Valge-Archer V, Feldmann M, Oppermann U. Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function Front Immunol. 2021 Feb 26;12:626255._x000D_ 7: He MY, Halford MM, Liu R, Roy JP, Grant ZL, Coultas L, Thio N, Gilan O, Chan YC, Dawson MA, Achen MG, Stacker SA. Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy Commun Biol. 2021 Jul 15;4(1):878._x000D_ 8: Lucas X, G√ºnther S. Targeting the BET family for the treatment of leukemia Epigenomics. 2014 Apr;6(2):153-5._x000D_ 9: Kothapalli J, Prasad Uppu V, Munikumar M, Kshirsagar SV, Afshan Jabeen S, Sivanarayana G. Structural insights of novel mutational frames in Bromodomain Containing-2 gene (BRD2) in juvenile myoclonic epilepsy: bed, bench, and laptop profiles Epilepsy Behav. 2023 Jul;144:109282._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32693114">10: Spriano F, Stathis A, Bertoni F. Targeting BET bromodomain proteins in cancer: The example of lymphomas Pharmacol Ther. 2020 Nov;215:107631. </a>_x000D_ _x000D_ <strong>Products Related to Anti‚ÄìBRD2 Polyclonal Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>
Product Specifications
CAS Number
9007-83-4
Short Description
Catalog Number: B2019147 (50 µL)
Weight
0.15
Length
2
Width
0.5
Height
0.5
Frequently Asked Questions
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