RY785
RY785 is a potent and selective voltage-gated potassium (KV2) channel inhibitor with an IC50 of 0.05 μM for KV2.2. RY785 has analgesic activity[1].
Product Specifications
CAS Number
1393748-80-5
Product Name Alternative
(±)-Norverapamil (hydrochloride); D591 (hydrochloride)
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ry785.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C2N=C(C3=CSC=N3)NC2=C1)C(C)CC4=CC=CC(OC)=C4
Molecular Formula
C21H20N4O2S
Molecular Weight
392.47
References & Citations
[1]Herrington J, et al. Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80 (6) :959-64.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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