DOPE-Mal

DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Product Specifications

CAS Number

[2295813-15-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Liposome

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dope-mal.html

Purity

98.68

Smiles

C(CC(NCCOP(OC[C@@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)(=O)O)=O)N1C(=O)C=CC1=O

Molecular Formula

C48H83N2O11P

Molecular Weight

895.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Ballesteros U, González-Ramirez EJ, de la Arada I, et al. Effects of a N-Maleimide-derivatized Phosphatidylethanolamine on the Architecture and Properties of Lipid Bilayers. Int J Mol Sci. 2023;24 (23) :16570.