DOPE-Mal
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Product Specifications
CAS Number
2295813-15-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dope-mal.html
Purity
98.68
Smiles
C(CC(NCCOP(OC[C@@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)(=O)O)=O)N1C(=O)C=CC1=O
Molecular Formula
C48H83N2O11P
Molecular Weight
895.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Ballesteros U, González-Ramirez EJ, de la Arada I, et al. Effects of a N-Maleimide-derivatized Phosphatidylethanolamine on the Architecture and Properties of Lipid Bilayers. Int J Mol Sci. 2023;24 (23) :16570.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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