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Anti-Mouse IFNγR/CD119 Antibody (GR-20)

Selected Variant

HY-P990233-01

Size: 1 mg

Anti-Mouse IFNγR/CD119 Antibody (GR-20) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IFNγR/CD119.Anti-Mouse IFNγR/CD119 Antibody (GR-20) reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. Anti-Mouse IFNγR/CD119 Antibody (GR-20) blocks the binding of IFNγ to CD119 therefore inhibiting IFNγ signaling. Anti-Mouse IFNγR/CD119 Antibody (GR-20) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma and C. trachomatis infected genital tract inflammation[1][2].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

IFNAR

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-ifnγr-cd119-antibody-gr-20.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

[Anti-MouseIFNγR/CD119Antibody(GR-20)]

Molecular Weight

(150 kDa)

References & Citations

[1]Vicetti Miguel RD, et al. Intravaginal Chlamydia trachomatis Challenge Infection Elicits TH1 and TH17 Immune Responses in Mice That Promote Pathogen Clearance and Genital Tract Damage. PLoS One. 2016 Sep 8;11 (9) :e0162445.|[2]Montfoort N, et al. NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines. Cell. 2018 Dec 13;175 (7) :1744-1755.e15.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

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