PPP2R5D Recombinant Rabbit Monoclonal Antibody [PSH01-21]
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the PPP2R5D gene. Mutations in PPP2R5D cause Jordan's Syndrome. The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
PPP2R5D
Swiss Prot
Q14738 Human
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human PPP2R5D aa 107-602 / 602.
Isotype
IgG
Clone
PSH01-21
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
A431 cell lysate, HeLa cell lysate, HepG2 cell lysate, MCF7 cell lysate, 293T cell lysate, Jurkat cell lysate, human brain tissue lysate, A431.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 70 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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