L-Glutamic acid-15N
Product Specifications
UNSPSC Description
L-Glutamic acid-15N is the 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[1].
Target Antigen
Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-glutamic-acid-15n.html
Solubility
H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
OC(CC[C@H]([15NH2])C(O)=O)=O
Molecular Weight
148.12
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14608S2/L-Glutamic-acid-15N-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14608S2/L-Glutamic-acid-15N-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
21160-87-2
Available Sizes
Curated Selection
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