7-Hydroxyneolamellarin A
7-Hydroxyneolamellarin A is a natural product that could be derived from sponge Dendrilla nigra. 7-Hydroxyneolamellarin A is a potent hypoxia-inducible factor-1α (HIF-1α) inhibitor. 7-Hydroxyneolamellarin A attenuates the accumulation of hypoxia-inducible factor-1α (HIF-1α) protein and inhibits vascular epidermal growth factor (VEGF) transcriptional activity. 7-Hydroxyneolamellarin A can be used in research of cancer[1].
Product Specifications
CAS Number
[959662-26-1]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase; VEGFR
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7-hydroxyneolamellarin-a.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C(O)C(N2C=C(C3=CC=C(O)C=C3)C(C4=CC=C(O)C=C4)=C2)=O)C=C1
Molecular Formula
C24H19NO5
Molecular Weight
401.41
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10330/7-Hydroxyneolamellarin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10330/
Scientific Category
Natural Products
Clinical Information
No Development Reported
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