Diazo Biotin-PEG3-alkyne
Product Specifications
UNSPSC Description
Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/diazo-biotin-peg3-alkyne.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NCCOCCOCCOCCNC(C1=CC=C(/N=N/C2=CC(CCNC(CCOCC#C)=O)=CC=C2O)C=C1)=O)CCCC[C@@H]3SC[C@]([C@]3([H])N4)([H])NC4=O
Molecular Weight
795.94
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140925/Diazo-Biotin-PEG3-alkyne-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140925/Diazo-Biotin-PEG3-alkyne-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1884349-58-9
Available Sizes
Curated Selection
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