Bismuth subnitrate

Bismuth subnitrate (Bismuth(III) oxynitrate) is a simple and efficient catalyst for the synthesis of methyl ketone by martensitic acetylene hydration reaction. When Bismuth subnitrate is intraperitoneally injected into mice, the distribution characteristics of bismuth (Bi) in the brain are similar to those of other exogenous metals such as mercury, silver and gold. Bismuth subnitrate has antibacterial activity, which can inhibit the growth of Staphylococcus aureus and Escherichia coli. Bismuth subnitrate is effective orally and can be used for the study of gastrointestinal diseases, which has protective effect on alcoholic gastric ulcer in rats[1][2][3][4].

[1]Szécsényi Z, et al. Bismuth Subnitrate-Catalyzed Markovnikov-Type Alkyne Hydrations under Batch and Continuous Flow Conditions. Molecules. 2021;26(10):2864. Published 2021 May 12. |[2]Notcovich S, et al. Effect of bismuth subnitrate on in vitro growth of major mastitis pathogens. J Dairy Sci. 2020 Aug;103(8):7249-7259.|[3]Ross JF, et al. Distribution of bismuth in the brain after intraperitoneal dosing of bismuth subnitrate in mice: implications for routes of entry of xenobiotic metals into the brain. Brain Res. 1996 Jul 1;725(2):137-54.|[4]Pugh S, et al. Endogenous prostaglandin E2 synthesis preserved following cytoprotection by Roter (bismuth subnitrate) in the rat alcohol model of gastric ulceration. Br J Exp Pathol. 1988 Dec;69(6):833-8.