L-703606
Product Specifications
UNSPSC Description
L-703606 is a potent, selective antagonist of NK1 receptor. L-703606 can be used for study of gastric acid secretion[1][2].
Target Antigen
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-703606.html
Smiles
IC(C=CC=C1)=C1CN[C@@H](C2CCN3CC2)[C@@H]3C(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Weight
508.44
References & Citations
[1]Minowa S, et al. Role of neuropeptide receptor systems in vanilloid VR1 receptor-mediated gastric acid secretion in rat brain. Eur J Pharmacol. 2004;486(3):317-324.|[2]Francis BE, et al. Radioiodinated L-703,606: a potent, selective antagonist to the human NK1 receptor. Appl Radiat Isot. 1994;45(1):97-103.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117216/L-703606-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117216/
Clinical Information
No Development Reported
CAS Number
144425-84-3
Curated Selection
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