Antifungal agent 91

Antifungal agent 91 (compound 1) is a dihydroflavonol that can be isolated from the leaves of Artocarpus elasticus. Antifungal agent 91 is a PTP1B inhibitor with an IC50 value of 0.17 μM. Antifungal agent 91 has antifungal activity[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Phosphatase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/antifungal-agent-91.html

Solubility

10 mM in DMSO

Smiles

OC1=CC2=C(C=CC(C)(C)O2)C3=C1C([C@H](O)[C@@H](C4=CC=CC=C4)O3)=O

Molecular Formula

C20H18O5

Molecular Weight

338.35

References & Citations

[1]Abdul Bari Shah, et al. Analogues of Dihydroflavonol and Flavone as Protein Tyrosine Phosphatase 1B Inhibitors from the Leaves of Artocarpus elasticus. ACS Omega 2024, 9, 8.