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Antifungal agent 91

Antifungal agent 91 (compound 1) is a dihydroflavonol that can be isolated from the leaves of Artocarpus elasticus. Antifungal agent 91 is a PTP1B inhibitor with an IC50 value of 0.17 μM. Antifungal agent 91 has antifungal activity[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Phosphatase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/antifungal-agent-91.html

Solubility

10 mM in DMSO

Smiles

OC1=CC2=C(C=CC(C)(C)O2)C3=C1C([C@H](O)[C@@H](C4=CC=CC=C4)O3)=O

Molecular Formula

C20H18O5

Molecular Weight

338.35

References & Citations

[1]Abdul Bari Shah, et al. Analogues of Dihydroflavonol and Flavone as Protein Tyrosine Phosphatase 1B Inhibitors from the Leaves of Artocarpus elasticus. ACS Omega 2024, 9, 8.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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