PDE4-IN-16
PDE4-IN-16 (compound 27) is a PDE4 inhibitor with an IC50 value of 3.61 μM. PDE4-IN-16 can be used for the research of inflammatory diseases and central nervous system (CNS) disorders involving elevated levels of cytokines[1].
Product Specifications
CAS Number
[223500-15-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pde4-in-16.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C(F)(F)F)N(C2=CC=C(N)C=C2)N=C1)OCC
Molecular Formula
C13H12F3N3O2
Molecular Weight
299.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Timothy J. Martins, et al. Pyrazole cyclic amp-specific pde inhibitors. .U.S. WO2001046172, 2001-06-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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