3-O-Methyl-DL-DOPA

3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency[1][2][3][4].

Product Specifications

CAS Number

[7636-26-2]

Product Name Alternative

3-Methoxytyrosine

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/3-o-methyl-dl-dopa.html

Purity

99.94

Solubility

H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC(CC1=CC=C(O)C(OC)=C1)C(O)=O

Molecular Formula

C10H13NO4

Molecular Weight

211.22

Precautions

H302, H315, H319

References & Citations

[1]Darin N, et al. Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B6-Dependent Epilepsy. Am J Hum Genet. 2016 Dec 1;99 (6) :1325-1337.|[2]Ormazabal A, et al. Pyridoxal 5'-phosphate values in cerebrospinal fluid: reference values and diagnosis of PNPO deficiency in paediatric patients. Mol Genet Metab. 2008 Jun;94 (2) :173-7. |[3]Abdenur JE, et al. Aromatic l-aminoacid decarboxylase deficiency: unusual neonatal presentation and additional findings in organic acid analysis. Mol Genet Metab. 2006 Jan;87 (1) :48-53. |[4]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39 (35) :5709-5720.