LN5P45

LN5P45 is an OTUB2 inhibitor (IC50: 2.3 μM) . LN5P45 induces monoubiquitination of OTUB2 on lysine 31. LN5P45 can be used for research of tumor progression and metastasis[1].

Product Specifications

UNSPSC

12352005

Target

Cathepsin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ln5p45.html

Concentration

10mM

Purity

99.05

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC=CC([C@H]2C[C@@H]2C(NNC(CCl)=O)=O)=C1

Molecular Formula

C13H15ClN2O2

Molecular Weight

266.72

References & Citations

[1]Gan J, et al. Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2. ACS Chem Biol. 2023 Aug 29.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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