Quinupristin

Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2].

Product Specifications

CAS Number

[120138-50-3]

UNSPSC

12352209

Hazard Statement

H315, H319, H320

Target

Antibiotic; Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/quinupristin.html

Purity

98.71

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C([C@](N(C([C@@](CCC1)([H])N1C([C@H](NC2=O)CC)=O)=O)C)([H])CC3=CC=C(N(C)C)C=C3)N(C[C@@H](CS[C@H]4C(CC5)CCN5C4)C6=O)[C@](C6)([H])C(N[C@@H](C7=CC=CC=C7)C(O[C@@H]([C@@H]2NC(C(N=CC=C8)=C8O)=O)C)=O)=O

Molecular Formula

C53H67N9O10S

Molecular Weight

1022.22

Precautions

H315, H319, H320

References & Citations

[1]Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent) . 2000 Jan;13 (1) :83-6.|[2]Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel) . 2019 Aug 21;8 (3) .