IMAC2 (hydrochloride)
IMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD50 of 15000 nM. iMAC2 hydrochloride shows anti-apoptotic effect. iMAC2 hydrochloride blocks cytochrome c release[1].
Product Specifications
CAS Number
335166-00-2
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/imac2-hydrochloride.html
Purity
93.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(CN1CCNCC1)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3.Cl.Cl
Molecular Formula
C19H22Br2Cl2FN3
Molecular Weight
542.11
Precautions
H315, H319, H320
References & Citations
[1]Peixoto PM, et al. MAC inhibitors suppress mitochondrial apoptosis. Biochem J. 2009 Oct 12;423 (3) :381-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
HIVEP2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
