Cedrelone

Cedrelone, a limonoid, is a Phenazine biosynthesis-like domain-containing protein (PBLD) activator. Cedrelone induces cancer cell apoptosis, and possess antitumor effects[1].

Product Specifications

CAS Number

[1254-85-9]

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cedrelone.html

Solubility

10 mM in DMSO

Smiles

C[C@]12[C@]34[C@]([C@H](C5=COC=C5)C[C@@]3([H])O4)(CC[C@]1([H])[C@@]6(C(C(C)(C(C=C6)=O)C)=C(C2=O)O)C)C

Molecular Formula

C26H30O5

Molecular Weight

422.51

References & Citations

[1]Jiansong Wu, et al. Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1. Exp Ther Med. 2019 Dec;18 (6) :4209-4220.